Can a colloid mill for nanoparticle preparation reach true nanoscale particle sizes?

A colloid mill for nanoparticle preparation can reduce particles into the low micron and, in favorable formulations, upper nanometer range, though it typically doesn’t reach the finest nanoscale sizes achievable with high-pressure homogenizers or media mills. It’s often used as a pre-reduction step before finer processing, lowering particle size enough to make subsequent nanoscale processing more efficient.